KnowNow™ COVID-19 Antigen Test – the true infectivity test

Sensitivity is not really the correct terminology for antigen testing, especially for testing in the field – what you really need to know is the Level of Detection (LoD) as this tells you how many antigens there need to be in a sample, for the test to be able to detect them and give a true positive result.

Because the Know Now™ test uniquely detects the spike protein and the virus is covered in lots of spikes, it has many more chances to detect each virus. That is the reason why the Know Now™ test can detect down to such low levels. The limit of detection is evidenced- to be 5 x 10² PFU/ml, which is 500 virus per ml of saliva.

The sensitivity means how well the test correctly detects the presence of the antigen and the KnowNow™ SARS-CoV-2 Rapid Antigen Test has an overall diagnostic sensitivity of 95.6% (95% CI 91.1-98.2%).

The specificity of the KnowNow™ SARS-CoV-2 Rapid Antigen Test is over >99.9% (95%CI : 98.6-100%) (specificity means the number of times the test will correctly identify true negatives, ie no false positives) Independent data evidences our test has not produced any false positives across hundreds of samples, however 100% is not something we would claim – lets just say it’s greater than 99.9%